Get quick access to your product right after purchase—no wait times.
Estimated to be delivered 0-24 H
Rest assured with our E-books digital products—delivered instantly via email! We stand by the quality of our digital offerings, but if you're not satisfied, we offer a hassle-free return policy.
You can request a refund for most digital purchases within 30 days of delivery. If you encounter any issues or if the product doesn't meet your expectations, simply contact our support team.
Although these digital products aren't physically returned, your satisfaction is our priority. Our team will work with you to ensure a smooth resolution or provide a refund promptly to your original payment method.
Shop with confidence! Enjoy the assurance of secure transactions with PayPal, a trusted and globally recognized payment gateway. Benefit from the safety and coverage of PayPal Buyer Protection, ensuring your purchase is secure and protected. Pay seamlessly with your credit or debit card through PayPal, providing you with an additional layer of security and convenience. Your peace of mind is our priority, and with PayPal, your transactions are backed by industry-leading safety measures and buyer guarantees.
Xin Zhang Editor Biological Effects of Static Magnetic Fields Second Edition Biological Effects of Static Magnetic Fields Xin Zhang Editor Biological Effects of Static Magnetic Fields Second Edition Editor XinZhang CASKeyLaboratoryofHighMagnetic FieldandIonBeamPhysicalBiology HighMagneticFieldLaboratoryof ChineseAcademyofSciences(CHMFL), HFIPS,CAS Hefei,Anhui,China ISBN978-981-19-8868-4 ISBN978-981-19-8869-1 (eBook) https://doi.org/10.1007/978-981-19-8869-1 ©TheEditor(s)(ifapplicable)andTheAuthor(s),underexclusivelicensetoSpringerNatureSingapore PteLtd.2017,2023 Thisworkissubjecttocopyright.AllrightsaresolelyandexclusivelylicensedbythePublisher,whether thewholeorpartofthematerialisconcerned,speci?callytherightsofreprinting,reuseofillustrations, recitation, broadcasting, reproduction on micro?lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilarmethodologynowknownorhereafterdeveloped. Theuseofgeneraldescriptivenames,registerednames,trademarks,servicemarks,etc.inthispublication doesnotimply,evenintheabsenceofaspeci?cstatement,thatsuchnamesareexemptfromtherelevant protectivelawsandregulationsandthereforefreeforgeneraluse. The publisher, the authors, and the editorsare safeto assume that the adviceand informationin this bookarebelievedtobetrueandaccurateatthedateofpublication.Neitherthepublishernortheauthorsor theeditorsgiveawarranty,expressedorimplied,withrespecttothematerialcontainedhereinorforany errorsoromissionsthatmayhavebeenmade.Thepublisherremainsneutralwithregardtojurisdictional claimsinpublishedmapsandinstitutionalaf?liations. ThisSpringerimprintispublishedbytheregisteredcompanySpringerNatureSingaporePteLtd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore Abstract: With the development of magnet technology, the potential impacts of magnetic ?elds on human health have caused increasing concerns. On the other hand, although permanent magnets have been used in magnetotherapy a long time ago, their effectiveness has always been debated. This is partially due to the discrepancy in reported static magnetic ?eld (SMF) bioeffects, as well as an incomplete understanding about the underlying physical and biological mechanisms. Fortunately, recent conceptual and technological advances have revealed that the previously reported inconsistencies are mainly caused by experimental setup variations, such as magnetic ?eld type, strength, distribution, treatment procedure as well as magnetic properties of various biological samples. The purpose of this book is to review current scienti?c evidence and summarize the emerging topic about the effects of SMFs on biological samples ranging from single molecules, subcellular compartments, cells to whole organisms. We will also summarize reported effects of SMFs on cancer, the immune and nervous system, bone and diabetes, etc. We realize that the ambiguities in this ?eld can be resolved, or at least much reduced by combining advanced techniques and concepts in interdisciplinary research, as well as standardized double-blind experiments and data analysis. These will not only help clarify most dilemmas in this ?eld, achieve a better understanding of the underlying mechanisms, but also enable future rational design and applications of SMFs in clinical diagnosis and therapy. Preface Withthedevelopmentofmoderntechnology,peopleareexposedtovarioustypesof magnetic ?elds, which include static magnetic ?eld (SMF), whose magnetic ?ux densityanddistributiondonotchangeovertime,aswellastime-varying magnetic ?eldsofdifferentfrequencies.ThemostcommonlyseenSMFsincludethemoderate SMFs generated by permanent magnets that exist everywhere, and higher SMFs generated by the core component of magnetic resonance imaging (MRI) machines formedicaldiagnosis(mostclinicalandpreclinicalMRIsare~0.5–9.4T).Accord- ingly, WHO (World Health Organization) and ICNIRP (International commission on nonionizing radiation protection) have published guidelines for the SMF expo- sureofhumanbodiestoensurethatpeoplearenotoverexposed.Ontheotherhand, magnetictherapy,althoughnotinthemainstreammedicine,hasbeenwidelyusedby manypeopleworldwideasalternativeorsupplementarytreatments.Thegoalofthis bookistosummarizecurrentscienti?cevidenceforthebiologicaleffectsofSMFs, including the observed phenomenon, their underlying mechanisms, as well as the studylimitations.Althoughthecurrentliteratureconcerningbioeffectsofmagnetic ?elds is replete with reports that are often not reproducible by other independent labs, we found that it is mostly caused by magnetic ?eld parameter and biological samplevariations,aswellasaninsuf?cientunderstandingofthismultidisciplinary andinterdisciplinaryareathatinvolvesbiology,physics,chemistry,andengineering. Moreover, the potential experimenter bias may also be a nonnegligible factor. Therefore, we encourage people to not only perform double-blinded analysis in independentstudies,butalsoclearlydescribealltheexperimentaldetailsaboutthe magnetic ?eld, biological samples, and the experimental procedure which will be crucialforpeopletoperformfurthersubjectiveanalysisandmechanisticinvestiga- tions.Itshouldbementioned thatwewill notcover magneticnanoparticle studies, whichhavepromisingtherapeuticapplicationpotentialsinmedicine;wewillfocus on the externally applied SMFs on human and animal objects, as well as their magnetic properties, but not elaborate on the weak magnetic ?elds produced by theelectriccurrentsinourbrain,heart,ormuscle,whichisanotherpromisingnew area formedicalapplications. We trytocover most aspects of biological effects of vii viii Preface SMFsbutalsowanttoapologizeforanymissedresearch?ndingsthathavenotbeen includedinthisbook.Ourgoalistryingtoprovidepeoplewithanoverviewofthe currentunderstandingofthebiologicaleffectsofSMFsandhopetoencouragemore scientists to get involved in this ?eld so that we can get a clearer view in the near future. Hefei,China XinZhang Contents 1 MagneticFieldParametersandBiologicalSampleDifferences ThatLeadtoDifferentialBioeffects. . . . . . . . . . . . . . . . . . . . . . . . . 1 XinZhang 2 StaticMagneticFieldDirection-InducedDifferentialBiological Effects. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31 BiaoYuandXinZhang 3 MagneticPropertiesofBiologicalSamples. . . . . . . . . . . . . . . . . . . 49 RuowenGuo,LeiZhang,HanxiaoChen,HaifengDu,ZheQu, andXinZhang 4 MolecularMechanismsforElectromagneticFieldBiosensing. . . .. 75 KrisDammen-Brower,AviSardana,andKevinJ.Yarema 5 ControllingCellMembranePotentialwithStaticNonuniform MagneticFields. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 VitaliiZablotskii,TatyanaPolyakova,andAlexandrDejneka 6 ImpactofStaticMagneticFieldsonCells. . . . . . . . . . . . . . . . . . . . 133 XinmiaoJiandXinZhang 7 ImpactofSMFsonMicroorganisms,Plants,andAnimals. . . . . . . 187 BaolinYang,LeiCheng,ZichengLiu,YananZhao,andAnXu 8 StaticMagneticFieldsonHumanBodies. . . . . . . . . . . . . . . . . . . . 239 XinZhang 9 PotentialApplicationsofStaticMagneticFieldsinCancer Treatment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 XinZhang ix x Contents 10 EffectsofStaticMagneticFieldsonDiabetesand ItsComplications. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 299 ChuanlinFeng,BiaoYu,andXinZhang 11 ImpactsofStaticMagneticFieldonBoneHealth. . . . . . . . . . . . . . 321 HuanhuanLv,JianchengYang,andYanruXue 12 EffectsofStaticMagneticFieldsontheImmuneSystem. . . . . . . . . 337 XinyuWangandXinZhang 13 BiologicalEffectsofStaticMagneticFieldsontheNervous System. . . . . .. . . . . . . .. . . . . . . .. . . . . . . .. . . . . . . .. . . . . . . .. 355 YueLvandXinZhang 14 TheBiologicalEffectsofLong-TermStaticMagneticField Exposure. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377 HanxiaoChenandXinZhang 15 Prospects,Pitfalls,andOpportunitiesforHumanStaticMagnetic FieldTherapy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 397 PaigeEplerandKevinJ.Yarema
Experience immediate satisfaction with our Ebooks digital products! Once your purchase is complete, your product is promptly delivered via email, ensuring zero wait times. Anticipate receiving your digital delivery within 0-24 hours, granting you rapid access to our premium digital offerings. Embrace efficiency with Ebooks—swiftly delivered straight to your inbox.
We are committed to your satisfaction with our Ebooks digital products. If, for any reason, you're unsatisfied, we offer a hassle-free return policy. You can request a refund for most digital purchases within 30 days of delivery. Contact our dedicated support team in case of any issues or if the product doesn't meet your expectations.
As these digital products aren't physically returned, your contentment remains our priority. Our team will diligently collaborate with you to ensure a smooth resolution or promptly process a refund to your original payment method. Your satisfaction is at the core of our commitment.
Thanks for subscribing!
This email has been registered!